Question

Suppose we identify 50 women 50 to 54 years of age who have both a mother and a sister with a history of breast cancer. Five of these women themselves have developed breast cancer at some time in their lives. If we assume that the expected prevalence rate of breast cancer in women whose mothers have had breast cancer is 4%, does having a sister with the disease add to the risk? Explain.

Answer 1

I would say no.

The sisters are just equally in danger as the original women because they both have mothers who have breast cancer themselves.