Answer:
Most TP53 mutations change single amino acids in the p53 protein, which leads to the production of an altered version of the protein that cannot control cell proliferation and is unable to trigger apoptosis in cells with mutated or damaged DNA. As a result, DNA damage can accumulate in cells
The fact that it's a renewable resource would be the only benefit. All of the others are disadvantages
Gene mutations can be passed on to future generations and drive natural selection. ... Gene mutations can be helpful, harmful, or neutral for an organism's survival. Only mutations that are helpful in the organism's environment would influence its survival and reproduction