Answer:
Role is defined below
Explanation:
A small GTP-binding protein, is an important module of the signal transduction pathway used by growth factors to initiate cell growth and differentiation. Cellular activation with growth factors such as epidermal growth factor (EGF) induces Ras to move from an inactive state linked to GDP to an active state linked to GTP. In recent times, a mixture of genetic and biochemical studies has resulted in the elucidation of a signaling pathway that leads from growth factor receptors to Ras. After joining EGF, the EGF receptor tyrosine kinase is activated, which leads to receptor auto phosphorylation in multiple tyrosine residues. Signaling proteins with homology domains Src 2 (SH2) then bind to these phosphorylated residues in tyrosine, initiating multiple signaling cascades. Distinct of these SH2 area proteins, Grb2, exists in the cytoplasm in a preformed complex with a second protein, Son of Sevenless (Sos), which can catalyze the Ras GTP / GDP exchange. After stimulation of the growth factor, the phosphorylated EGF receptor with tyrosine binds to the Grb2 / Sos complex and translocates it to the plasma membrane. It is believed that this translocation brings Sos closer to Ras, which leads to the activation of Ras. In dissimilarity, the insulin receptor does not bind Grb2 directly, but rather induces the tyrosine phosphorylation of two proteins, the substrate-1 insulin receptor and Shc, which bind to the Grb2 / Sos complex. Once Ras is activated, a cascade of protein kinases that are important in a myriad of growth factor responses is stimulated.
I believe it was Pangaea but I could be wrong
Answer:
The kinetic theory of matter (particle theory) says that all matter consists of many, very small particles which are constantly moving or in a continual state of motion.
Explanation:
hopes this helps :D
brainliest pls?
Answer:
Slab pull is the theory of plate movement which relies on the weight of the subducting crust.
Explanation:
Plate movement are the measure of motion of tectonic plates. As it is known that our earth crust is composed of different sizes of tectonic plates. So these plates can move depending upon the pressure exerting on it. So slab pull is one of the theories existing with plate movement. In this case, the movement of the plates occur due to the weight of the subducting crust. The subducting crust is the boundary between tectonic plates. So depending upon their weights, the slab pull theory works.
