This electrical signal start in the sinoatrial node generates an electrical impulse. From this, the signal passes through the atrioventricular node, which stops the signal for a brief moment and sends it through the muscle fibers of the ventricles, stimulating its contraction.
Explanation:
The electrical impulses generated by the myocardium stimulate the heartbeat. This electrical signal originates in the sinoatrial node located in the upper part of the right atrium. When the sinoatrial node generates an electrical impulse, it stimulates the contraction of the atria. From this, the signal passes through the atrioventricular node, which stops the signal for a brief moment and sends it through the muscle fibers of the ventricles, stimulating its contraction.
skin appendages can redirect and or stop the absorption of the drug as well as the physio-chemical properties of the drug itself that make it harder for the skin to absorb
