Question

HIV is the virus that causes AIDS. In the mid-1990s, researchers discovered an enzain protease. Once the enzyme's structure the active site and block it. If this strategy for stopping HIV infections were successful, it would be an example of what phenomenon? was known, researchers began looking for drugs that would fit into A noncompetitive inhibition B. denaturation C. allosteric regulation D. competitive inhibition

Answer 1

Answer:

The correct answer is D. competitive inhibition

Explanation:

Competitive inhibition occurs when a substance called inhibitor that resembles like substrate binds in place of substrate in the enzyme and inhibit the chemical reaction that can occur by binding of enzyme with substrate.

So in competitive inhibition, the inhibitor binds to enzyme because it might have a higher affinity for enzyme or the number of inhibitors is higher than the substrate. This binding prevents the formation of the enzyme-substrate complex by blocking the active sites of the enzyme.

So here if a drug can be found that could block the active site of enzymes that is coded by HIV then it would be the example of competitive inhibition.

Answer 2

Answer:  Option D

Explanation:

There are many steps included in the HIV cycle that can be interfered to stop the replication of virus.

One of the major step involved in it is proteolytic clevage of the polypeptide precursor into mature enzymes.

The HIV protease are competitive in nature which inhibits the activity of virus aspartyl protease.

This prevents the conversion of the HIV infection into its mature form. This process helps in the drug discovery for HIV.