The hemoglobin holoenzyme (active enzyme) is a complex of an iron ion and 4 subunits- 2 hemoglobin alpha and two hemoglobin beta. People with sickle cell disease have mutated beta hemoglobins. The mutation is a single nucleotide exchange, that changes the 6th amino acid of protein primary struture - a Glutamic acid into Valine. This one alteration changes the tree dimentional structure of hemoglobin beta so, that it forms lond fibres that disrupt the normal circular form of the red blood cells.
The most appropriate statement that is explaining the effect and cause during muscle contraction is. “The release of calcium ions causes myosin and actin to attach to each other.” The activation of muscles helps in the generation of muscles that send out the signals to the neurons.
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A. Sediment
Explanation:
As water flows, it both breaks down rocks and picks up soil. When the pieces of rock and soil are travelling in water, they are called sediment.