Answer:
Phase III
Explanation:
The given condition fall in the trial phase (Phase III) of cinical study which aims to:
- Determine drug's effectiveness (primary goal)
- Determine long-term drug safety
- Confirm findings
In Phase III, randomised, double-blind, placebo-controlled, parallel group study is majorly to evaluate the efficacy and safety of placebo in episodic migraine prevention in children (6 to < 12 years of age) and adolescents (12 to < 18 years of age).
The trial consists of four phases: screening; double-blind therapy period for 24 weeks in which placebo or Erenumab is given to subject as dose 1, dose 2 or dose 3 (based on the participant's body weight) once a month via subcutaneous injection; optional dose level blinded extension phase (40 weeks) which involves subjects recieve dose1, 2 and 3 of placebo, and at last it follows a safety follow-up phase for 12 weeks (after 16 weeks of the last dose of investigational drug).
Hence, the clinical phase is phase III.
The rapid release of air/ gas bubbles during cooling
I think the answer would be "A"
The muscles that contract (during cold or fright), the slanted hair follicle is pulled upright, dimpling the skin surface with goosebumps are called arrector pili muscle.
The arrector pili muscle are tiny muscle that attaches to the base of the hair follicle at one end and to the dermal tissue on the other end. When the body feels cold or fright the body generate heat and the arrector pili muscle contract all at once, that causes goosebumps on the skin.
The arrector pili muscle acts as the thermoregulator. Straight stand hair increases air trapping, so that the heat loss from the body decreases. The arrector pili muscle are mediated by the sympathetic nervous system.
To learn more about sympathetic nervous system here
brainly.com/question/12958051
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Mitochondria since it’s the power house of the cell where the energy for this one is produced
