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Given :
Calculate the carboplatin dose for a 60 year old man patient weighing 200 pounds.
The patient's serum creatinine is 1.2mg/dL with a target AUC of 6.
To Find :
The carboplatin dose.
Solution :
Carboplatin dose is given by :
![C.D = AUC\times [\dfrac{(140-age)\times ( weight \ in \ pounds)}{serum \ creatinine(mg/dL)\times7.2\times 2.2}+25]](https://tex.z-dn.net/?f=C.D%20%3D%20AUC%5Ctimes%20%5B%5Cdfrac%7B%28140-age%29%5Ctimes%20%28%20weight%20%5C%20in%20%5C%20pounds%29%7D%7Bserum%20%5C%20creatinine%28mg%2FdL%29%5Ctimes7.2%5Ctimes%202.2%7D%2B25%5D)
Putting all given values in above equation, we get :
![C.D = 6\times [(\dfrac{(140-60)\times ( 200)}{1.2\times72\times 2.2})+25]\\\\C.D =655.05\ mg](https://tex.z-dn.net/?f=C.D%20%3D%206%5Ctimes%20%5B%28%5Cdfrac%7B%28140-60%29%5Ctimes%20%28%20200%29%7D%7B1.2%5Ctimes72%5Ctimes%202.2%7D%29%2B25%5D%5C%5C%5C%5CC.D%20%3D655.05%5C%20mg)
Therefore, the carboplatin dose is 655.05 mg.
this isnt really a question but ok thanks for the fact
Explanation:
it's water because one can live without eating food two days although the person may be weak but when it comes to water one can't live without water for even an hour the person will absolutely die