Phenergan(promethazine) is generally used for allergies, motion sickness, and headaches. So theoretically you could. You'd have to check the dosages though.
Exercises that improve cardiovascular fitness and body composition do this because they increase your metabolism and increase your muscle mass. This makes you look better but more importantly it makes your body become more eficient and run more efficiently, with that it then lessens the chance of cardiovascular disease.
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While exercising with a friend can make it more motivating and fun, beginning a new exercise program requires a visit to your doctor.
The physician can help and guide you in assessing your fitness level and recommend (if necessary) you to professionals that will help in designing your fitness program. The doctor can also help monitor your progress and may assist in adjustments.
Thalassemia doesn't have a specific symptom or indication, it varies based on the severity of the sickness but the most common symptoms are: iron overload, increased risk of infection, and a decrease in growth.