Answer:
red blood cells (RBCs) misfolding and convert in sickle shapevfrom the donut with out hole shape.
<span>A point mutation that results in the substitution of one amino acid for another within a protein is a missense mutation.
</span>This type of mutation<span> is a change in one DNA base pair that results in the substitution of one amino acid for another in the protein made by a </span>gene<span>. </span>
Arrow a should point to muscle tissue, arrow B should point to an organ, arrow c should point to organ system.
