The correct order of central dogma is deoxyribonucleic acid (DNA) → ribonucleic acid (RNA) → Protein.
Central dogma refers to the two-step process by which information present in the DNA is passed into the proteins.
The two steps are:
Transcription: It is the first step in gene expression by which information in the form of the nucleotide sequence of DNA is copied into the nucleotide sequence of RNA. It is catalyzed by an enzyme RNA polymerase.
Translation: It is the process by which nucleotide sequence of RNA is decoded into the amino acid sequence of a polypeptide chain. Ribosomes serve as the site for translation.
Central Dogma is a term that refers to the two step process through which information flows from the sequence of DNA into a sequence of RNA (the process of transcription) and finally takes the form of proteins (the process of translation)
Francis Crick was the first scientist who proposed the term of "Central Dogma".
Significance of Central Dogma:
This is the process that ensures that genetic information of all living organisms is preserved and transmitted without any alteration or changes into their offspring.
It is a process that intricately explains the logical mechanism through which DNA stored in our chromosomes express themselves into functional forms called proteins.
This was the process which let us know the important roles of molecules like ribosomal RNA, transfer RNA and messenger RNA in the process of protein formation.
The process has immense importance in understanding the latest advances in RNA technology that can further help in investigation and diagnosis as well as treatment of many critical diseases.
