Yes it does the chemicals in whatever you are smoking are more than likely altered from what it originally was, therefore the chemicals start to taint the blood vessels and damage them permanently.
Answer:
They would all not work they all work together.
Basketball is preformed in this picture
See, if you don't brush your teeth regularly, they will rot and your teeth are so close to your brain that it won't make your brain feel any good at all! It can cause a lot of diseases!