A urine sample arrives in the laboratory for routine testing. The sample is placed at room temperature at 7 a.m. and will be tes
ted with the next large batch of samples due to arrive from the outpatient clinic at 11 a.m. How will the sample be affected by the storage time and temperature?
The main function of the kidney is the formation of urine. Three main important process of urine formation are glomerular filtration, tubular absorption and tubular secretion.
The sampling and testing of urine occurs in the laboratory. A urine sample is placed at 7 a.m. and is not tested till 11 a.m. at room temperature. This delay in testing will degrade the casts and the cells present in urine sample. The physical composition of the urine may also get changed.
Thus, the answer is casts and cells degrade in the sample.
Cholesterol (especially LDL*) tend to get into macrophages which migrate into blood vessels. Macrophages with cholesterol cannot get out of the vessels and stay there which causes a lipid mass in arteries. That causes atherosclerosis.
