First pass metabolism of a drug is said to occur when the concentration of a drug that is administered orally is significantly reduced before it reaches the systemic circulation.
First pass metabolism usually occur in the liver.
The routes of drug administration that avoid complete first pass metabolism are: sublingual, transdermal, rectal and inhalation.
Scientists think that dolphins and whales may have evolved from a common ancestor because they have similar anatomies.
<h3>What is a common ancestor?</h3>
A common means different animals now, have evolved from a single ancestor or animal.
These animals may share common characters and structures.
Whales, dolphins, and porpoises are evolved from a common ancestor; cetacean.
The animals that evolved from cetaceans are all aquatic, primitive cetaceans were amphibians too.
Thus, They have similar anatomies.
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