Fructose-1,6-bisphosphate is a feedforward <u>allosteric</u> activator of liver pyruvate kinase.
<h3>What is the role of fructose 1/6-Bisphosphate?</h3>
A crucial enzyme in gluconeogenesis is fructose 1,6-bisphosphatase (FBPase). It is a possible target for drugs used to treat type II diabetes. Additionally, the protein is linked to a rare genetic metabolic disorder, and certain cancer cells lack the activity of the enzyme FBPase, which encourages glycolysis and aids in the Warburg effect.
The following reaction is catalyzed by FBPase. The enzyme is controlled allosterically by several small molecules, including AMP and fructose-2,6-phosphate, which are negative regulators, and ATP, which is a positive regulator. Pyruvate kinase activity is activated when FBP attaches to the allosteric binding site on domain C of the enzyme. This conformational shift is brought on by a change in the enzyme's structure.
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Due to you inhaling through your nose, bacteria gets in the snot. if you pick your nose you're one opening up a canal that has a mucus lining to stop these bacteria, two ingesting the bacteria as well.<span />
Answer:
Scientists share habits of mind, that lead them to exploration and discovery. New ideas are generated by curiosity, skepticism, open-mindedness, and creativity.
Answer:
similar results in multiple tests of the claim
Explanation:
A scientific claim comprises of similar results in multiple tests of the claim.
Scientific methods include observation, performing experiments, inference etc.
A scientific claim is however said to be valid when the results of the experiment are reproducible multiple times in any part of the world. The results are usually shared with others to ensure that the several tests are conducted by different scientists to check its authenticity.
