What do you mean by responsible? Do you want to know the genetics behind it, what the surface markers do, or why they are metically important? I think I can help.
Small
components used to make or repair jewelry are called jewelry findings. Jewelry findings are basically
components, materials and elements such as clasps, pins, hooks, tabs etc that
can be used in making, assembling or repair a piece of jewelry.
It's the first one where it resist change in pH solutions by neutralizing :)