Its the difference between the y- values divided by the distance between the corresponding x values. Or its sometimes called rise / run.
Negative minus negative greater negative get rid of the ()
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This division question is asking how many 1/4 you can fit into 50 1/2.
We can fit 4 of them into 1 whole (4 x 1/4 = 1)
We can fit 8 of them into 2 wholes (8 x 1/4 = 2)
and so on.
But we have 50 1/2 wholes, so we would need 50 1/2 x 4.
The new number sentence is 50 1/2 x 4.