the Dependence stage this is when the drinker depends on alcohol
The best response would be No thanks, I don't want to drink alcohol.
Larry is taking a walk in the park. The pollen in the air makes him sneeze constantly. The line of defense that is his immune system exhibiting is that of "(A) first line of defense." There are only 3 lines of defense in the immune system. The first line of defense are a combination of physical and chemical barriers that prevent all types of foreign agents from penetrating the outer layer of the body. In this case, it is the nasal cavity.
When stimulated, the brain stem's sneeze center orders muscle contractions from esophagus to sphincter. That includes the muscles controlling the eyelids. Some sneezers even shed a few tears. Perhaps people close their eyes while sneezing to prevent the expelled particles from entering their eyes,
