Answer:
Human beings have a base biological need for emotional connection with other people. Throughout human evolution, being a part of a group of people was necessary for survival. Our distant ancestors could not survive alone outside in the harsh elements hunting for food and water and seeking shelter and safety. Humans have survived by being able to connect with other people in a manner which allowed them to remain within a group. Being seen as dangerous, selfish, or unable to connect and contribute to the group meant being ostracized and soon after, death.
Even today, without the dangers our distant ancestors faced, our biological systems are strongly geared toward social engagement. The only priority that trumps social engagement is physical survival. This means that our nervous systems are built to respond quickly and automatically, without any thought, to keep us alive AND in connection with other people. Some level of emotional connection is paramount to our survival and health. Feelings of loneliness, detachment, and isolation are not merely due to individual histories or personalities. They are built-in warning signs that we are missing life-sustaining connection with other people.
Explanation:
The public protector tasked with :
- investigation of misconduct in any state affairs and governments. This include the white collar crime by the high end government to the petty theft crime by the administration
- Protect public interest and Human Right
Because strep throat is a bacterial infection, your doctor will prescribe an antibiotic to treat it. These medications inhibit the spread of bacteria and infections. Several types of antibiotics are available. It's important that you finish your antibiotic treatment course to kill the infection completely.
Evidence suggests that cAMP response-element-binding protein (CREB) may be a final common target of antidepressant treatment.
Antidepressant medications work by binding to a number of monoamine neurotransmitter receptors and activating the cAMP signal transduction pathway. Chronic antidepressant therapy has been linked to the cAMP signalling system. Increases in cAMP cause the cAMP response element-binding protein(CREB) to be phosphorylated more frequently via increased receptor adenylate cyclase activity .
CREB mediates transcriptional responses to increased cAMP levels by attaching to cAMP response element (CRE) sites.In order to prevent recurring episodes, treatment for depression should maintain therapeutic efficacy while also addressing behavioural symptoms and indicators of the illness. One important modulator of the transcriptional effects of antidepressants may be CREB.
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