The correct answer is: "Unexpected, related or possible related to the research, suggests the research puts subjects or others at greater risk"
The OHRP defines an unticipated problem in the scenario of a research involving human participants. Defining the problem as unanticipated means that it was not foreseen at all when detailing the possible risks for the parcipants of the study on when those were asked to sign a consent form. It is also unanticipated in the sense that the problem which have aroused does not match in terms of likelihood with the characteristics of the specific individual suffering it.
Such term does not refer to some inconvenience with minimum consequences, but it suggest that the problem occurring affects the research subjects or others and places them at a greater risk of harm - physical, psychological, economic ,etc.- than was anticipated before the research.
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The answer to this question is <span>when two variables are correlated, we cannot be sure what is causing the correlation.
For example, let's there is a study that found an increase in consumption in tofu lead to an increase in breast cancer.
Even if it's true that those two really correlated (let's just assume it), we wouldn't be able to know why it is correlated without further researches.</span>
