Both Haworth and chair conformations can be used to represent disubstituted cyclohexanes. However, <u>the energies for each chair conformation are different</u>, thus one conformation will be more favored than the other.
For the 1,3-cyclohexanes, the most stable conformation of the <em>cis</em> isomer has both methyl groups in equatorial positions. Any conformation of the <em>trans</em> isomer puts a methyl group in an axial position. Therefore, the <em>trans</em> isomer has more energy than the <em>cis</em> isomer. We need to remember, though, that <em>cis </em>and <em>trans</em> isomers can’t be interconverted and there is no equilibrium between these.
In the graph you can so that two of the shapes ae fully black, that means that they are color blind, the half colored ones means they are a carrier but they aren't color blind. So two males in the offspring are color blind.