Life and death are complex things. Life is the existence of something and death is the end. They go hand in hand. Without one you cannot have the other. To live means to die and to die means you have lived.
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If the live enzyme fructose 1,6- bisphosphatase defect is occured and this results in an abnormally high levels of lactate in the blood plasme this will result into the lactate will accumulate into the blood.
What is the work of fructose 1,6-biphosphatase enzyme?
In the liver, gluconeogenesis converts lactate to glucose. If FBPase-1 is defective, lactate cannot enter the gluconeogenic pathway in hepatocytes, building up in the blood.
A crucial enzyme in gluconeogenesis is fructose 1,6-bisphosphatase (FBPase). It is a possible target for drugs used to treat type II diabetes. Additionally, the protein is linked to a rare genetic metabolic disorder, and certain cancer cells lack the activity of the enzyme FBPase, which encourages glycolysis and aids in the Warburg effect.
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A genotype is a genetic makeup of an organism that determines the phenotype, a characteristic that is expressed. E.g. genotype of blood type OB is made up of two alleles Io and Ib , this results in the person’s blood type to be B, the phenotype
