Question

A 35-year-old man is at his follow-up visit for GERD. Antacids have not been effective for his reflux, and the health care provider is prescribing a proton pump inhibitor. Why might the provider prescribe a PPI rather than an H2RA?
A. PPIs suppress acid more strongly and for a longer time.
B. Drug Therapy: Rationales for Nursing Practice.
C. Drug Therapy for Peptic Ulcer Disease and Gastroesophageal Reflux Disease.

Answer 1

Answer: A) PPIs suppress acid more strongly and for a longer time.

Explanation:

Gastroesophageal reflux disease (GERD) is defined as a disease of digestive system in which stomach acid comes up into the esophagus for long-term and causes irritation in the esophagus.

Gastroesophageal reflux disease (GERD) can be treated by using anatcid (Histamine type-2 receptor antagonist- H2RA) and proton pump inhibitor (PPI).

Both medications work in same manner by decreasing and blocking the production of stomach acid. but antacid works for a short time period while PPI is effective for long time and has stronger effect.

In this case also anatcid is non-effective for the reflux and provider prescribe PPIs which has stronger ability to suppress stomach acid for longer time.

The correct option is A.