South African people are vaccinated with Yellow fever. First, SA is strict in the implementation proof of vaccination in travelers coming in the country. The vaccination card must show vaccination at least ten days prior to travel. This is to prevent reintroduction of the disease to SA people. Second, In the list of Center for Disease Control, South Africa is not included in the countries with an endemic Yellow fever which means that the disease is wiped out if not controlled through vaccination.
Answer:
The cell interior would experience higher than normal Na+ concentrations and lower than normal K+ concentrations.
Explanation:
Na+/K+ ATPase exists in two forms: Its phosphorylated form has a high affinity for K+ and low affinity for Na+. ATP hydrolysis and phosphorylation of the Na+/K+ pump favor the release of Na+ outside the cell and binding of K+ ions from the outside of the cell. Dephosphorylation of the pump increases its affinity for Na+ and reduces that for K+ ions resulting in the release of K+ ions inside the cells and binding to the Na+ from the cells.
The presence of ATP analog would not allow the pump to obtain its phosphorylated form. Therefore, Na+ ions would not be released outside the cells. This would increase the Na+ concentration inside the cell above the normal. Similarly, the pump would not be able to pick the K+ from the outside of the cell resulting in reduced cellular K+ concentration below the normal range.
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