An application where you would prefer a parallel circuit over series would be a string of Christmas lights. If the light string is wired in parallel, when one bulb burns out, it would not effect the red of the string.
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Indeed, this is to be true as software is to programs and applications(apps) hardware is to physical computers such as hard drive, SSD, motherboard, ram, graphics card, ect...
The best defense against injection attacks is to develop secure habits and adopt policies and procedures that minimize vulnerabilities. Staying aware of the types of attacks you're vulnerable to because of your programming languages, operating systems and database management systems is critical.