Answer:
The three methods are: 1) Using H-Ras- SREBP- 2 Fusion proteins, the NH2 segment can be released by two sequentia
Explanation:
Sterol regulatory element binding proteins (SREBPs) are transcription factors attached to the endoplasmic reticulum. The NH2-segment, which activates transcription, is connected to membranes by a hairpin anchor formed by two transmembrane sequences and a short lumenal loop. Using H-Ras–SREBP-2 fusion proteins, we show that the NH2-segment is released from membranes by two sequential cleavages. The first, regulated by sterols, occurs in the lumenal loop. The second, not regulated by sterols, occurs within the first transmembrane domain. The liberated NH2-segment enters the nucleus and activates genes controlling cholesterol synthesis and uptake. Certain mutant Chinese hamster ovary cells are auxotrophic for cholesterol because they fail to carry out the second cleavage; the NH2-segment remains membrane-bound and transcription is not activated.
Answer:
All options are correct.
Explanation:
Fibers may be defined as the type of carbohydrate that cannot be digested by the body. Two main types of fiber are soluble fibers and the insoluble fibers.
Fibers play an important role in the body. Fibers manage the blood sugar level and prevent constipation. The fibers also helps in the reduction of the absorption of cholesterol in the body. Insoluble fibers prevent constipation and soluble fibers maintains blood sugar level.
Thus, all the given options are correct.
Answer:
C. A pharmacist has completed a higher level of education, and will take more responsibility on the job.
Explanation:
I calculated it logically
