Answer:
The miRNAs act as post-transcriptional silencers, as they are similar to specific mRNAs and regulate their stability and translation. They are small endogenous non-coding ribonucleic acid (RNA) molecules, with about 22 nucleotides, which act as regulators of gene expression in plants and animals, at the post-transcriptional level through the cleavage of a target messenger RNA (mRNA) or repression of translation.
In general, most miRNA genes are transcribed by RNA polymerase II in the nucleus in primary miRNAs (pri-miRNAs). Individually, a pri-miRNA can produce a single miRNA or contain groups of two or more miRNAs that are processed from a common primary transcript. These long pri-miRNA are cleaved by a complex comprising the double-stranded RNAse III enzyme (DROSHA) and its essential cofactor, the binding protein DGCR8 (DiGeorge Syndrome Critical Region 8 protein) in mammals. DROSHA contains two domains of RNAse III, each of which cleaves a strand of the RNA resulting in the precursor microRNA (pre-miRNA) with about 70 base pairs, which contains a double-stranded stretch and a single-stranded loop, forming a structure in clamp. The pre-miRNA is exported to the cytoplasm by the protein exportin-5 (XPO-5), where it is cleaved by DICER1, an RNAse III that assesses the 3 'and 5' ends of the pre-miRNA, generating a mature miRNA with about 22 nucleotides. The processing of pre-miRNA by Dicer promotes the unfolding of the RNA duplex in the form of a clamp. The position in the formation of the clamp can also influence the choice of tape.
Explanation:
Answer:
Thymine, which is often abbreviated to T or Thy, can also be referred to as 5-methyluracil. It is one of the pyrimidine bases found in the nucleic acid of DNA, along with adenine, guanine and cytosine (A, G and C). These bases are the building blocks of DNA and life form on earth.
Explanation:
can someone help me on my most recent question, its math and its multiple choice
Answer:
uuh, well, the guy that answers the questions with the link is a scammer and DO NOT click the link! it'll ask u to download stuff to ur computer/phone that you have no idea what it is-then u'll have to go and manually uninstall the things it made you download, which is such a pain. the guy also goes by many accounts that start with a b and has no profile pic, and if they answer the question, their answer is immediatly deleted but takes like a day for someone else to answer the question b/c it takes forever to process for that person's account/answer to be deleted-id k why- it just does
Mitotic spindles are microtubule-based structures that separate chromosomes during mitosis. So the cell would lack structure.
Answer:
lungs
explanation:
Asbestosis (as-bes-TOE-sis) is a chronic lung disease caused by inhaling asbestos fibers. Prolonged exposure to these fibers can cause lung tissue scarring and shortness of breath. Asbestosis symptoms can range from mild to severe, and usually don't appear until many years after continued exposure
