Answer:
A, C, D and E
Explanation:
In the assessment of legs, there are many systems that are combined for that part of the body to function optimally.
The reason that all the options are relevant in this question (except for B) specifically referring to legs, is that option B (the cardiovascular system) is not a main indicator of a problem with that part of the body specifically.
If something is wrong with the leg of a patient, there is a small likelihood of it being related to the cardiovascular system, because if the cardiovascular system is causing something to be wrong in the legs, it should not be limited to that section of the body. Hence, the other options are correct, but not option B.