No, because of the mass amount of fossil fuels used during the Industrial Revolution.
Explanation:
Hemophilia is a disease that is characterized by an abnormal blood clotting process. There are many different proteins that are involved in the clotting process and a single mutation or change in one of them could result in serious effects. Hemophilia is characterized by an abnormal version of one of the many proteins involved in the clotting process, the proteins that are commonly affected are the coagulation factor 8 or 9 (VIII or IX). These abnormal proteins are caused by a mutation in the gene (within the DNA) that codifies for the production of each protein. In other words, a mutation in the part of the DNA, (gene F8) will lead to a dysfunctional coagulation factor VIII and a mutation in the gene F9 will lead to a dysfunctional coagulation factor IX. Importantly, these mutations could be inherited and could cause hemophilia. Therefore, an error in the DNA and subsequently, an error in the protein will cause hemophilia. Finally, it is important to mention that there are other types of hemophilia that are not caused by the above-mentioned mutations, such as acquired hemophilia.
GAU to GAC is least likely to change phenotype of an organism.
<h3><u>Explanation</u>:</h3>
Phenotype of an organism is defined as the physical characteristics of an organism. This phenotype is dependent on the genotype of the organisms. This means the phenotypic characters are actually the expressions of the genes of the organisms. Now the genes are expressed in form of codons that are the three nitrogen base sequences. Each codon codes for a particular amino acid which in turn polymerises to from the protein which actually forms the phenotype of the organism.
Now there are 20 amino acids and 64 codons. Thus there are more than 1 codons for a single amino acid. So, if a codon is replaced by another codon which codes for same amino acid, then the phenotype is least likely to be affected.
Both the GAU and GAC codes for aspartic acid. So the phenotype won't be affected much by this mutation
The answer is the 1st statement.
Has varied greatly over time
