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mihalych1998 [28]
3 years ago
8

What role does the MutL protein play in DNA repair? (5 POINTS) It performs a proofreading function, similar to DNA polymerase, a

nd removes incorrect bases from the template DNA strand. It recognizes and binds to a pair of "mismatched" nucleotides, preventing their translation. It recognizes the newly-synthesized DNA strand (e.g., by detecting nicks), ensuring only it—and not the template strand—is repaired. It helps to link together regions of DNA, after an error has been removed via exonuclease.
Biology
1 answer:
Zinaida [17]3 years ago
5 0

Answer:

It recognizes and binds to a pair of "mismatched" nucleotides, preventing their translation.

Explanation:

Mut L protein is involved in mismatch DNA repair. MutL protein is complexed with MutS protein and the MutL-MutS complex recognizes all the mismatched base pairs present in the newly formed DNA strand. The complex can not recognize the "C-C" pairs. MutH protein joins the complex.

The MutH protein also has a site-specific endonuclease activity and cleaves the unmethylated DNA strand towards the 5' end of the guanine base in the GATC sequence to mark the strand for DNA repair. In this way, MutL protein, along with MutS and MutH proteins mark the mismatched DNA bases for repair so that they are not translated into a faulty protein.

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Why is nonpoint surface pollution is a greater threat and hazard than point source pollution
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Nonpoint source pollution is a greater hazard, because scientists are not able to identify a single location the pollution came from. It is harder to find a solution if they are unable to find the source.

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6 0
2 years ago
Which model of the universe did the ancient Greeks believe to be correct. This is for the subject of earth science
kow [346]

Answer:

The Greeks believed in the geocentric model of the universe.

According to this model, the Earth was present in the center whereas the Sun, moon, other planets etc revolved around it. According to Plato, the Earth was spherical in shape and it did not move. Greek philosophers, such as Aristotle and Plato, believed the Earth to be the center of the universe. All other heavenly bodies orbited around the Earth according to the Greek philosophers.

8 0
3 years ago
Which of the following is not associated with the renal corpuscle?
Black_prince [1.1K]
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3 0
3 years ago
An individual that is heterozygous for flower color and for height (PpTt) is test crossed. What is the phenotypic ratio of the o
MrRa [10]

Answer:

9:3:3:1

Explanation:

This type of crossing that involves two characters is referred to as dihybrid crossing. Generally, when there is a dihybrid crossing for heterozygous genes for both parents, the phenotypic ratio is usually 9:3:3:1 as shown in the figure in the attached document below.

Assuming the colour is White (P) and Black (p) and the

Height is Tall (T) and short (t)

The possible phenotypes will be in the ration

9 - White and Tall

3 - White and short

3 - Black and Tall

1 - Black and short

It should be noted that phenotypic ratio (phenotype) describes the outward appearance (what can be see physically) and not the genetic make-up. Thus, where there is a dominant character like P or T, the recessive characters are not considered to have been expressed.

Download docx
3 0
2 years ago
Gametes, which are sex cells, carry the alleles. Why must a gamete carry one allele (represented by a letter) from each gene? Me
ser-zykov [4K]

Answer:

Due to the law of independent assortment

Explanation:

In diploid species like humans, all somatic (body) cells have two complete sets of chromosomes, one chromosome inherited from the maternal gamete and one chromosome inherited from the paternal gamete. Each one of the homologous chromosomes contains one copy of each gene, or allele, such that one allele is inherited from each parent. According to the law of independent assortment, maternal and paternal chromosomes are independently assorted during meiosis, which means that different genes localized on different chromosomes are randomly distributed into gametes. In consequence, alleles of different genes are transmitted from parents to offspring independently of one another.

4 0
2 years ago
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