When insulin is deficient , GLUT4 transporters are not inserted into the cell membranes , glucose is not transported into the cells and the blood glucose concentration increases.
Insulin deficiency provides more amino acid and glycerol substrates for glucose synthesis ie increased gluconeogenesis .
With a deficiency of insulin, there is both increased hepatic glucose production through increased glycogenolysis and gluconeogenesis as well as decreased glucose use. The result is hyperglycemia.
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They flow in all directions
Answer:
The first stage is the Interface.
Explanation:
There are primarily two main stages in a cell cycle; but the first stage is the interface. This is a stage in which a cell grows and also replicates its DNA.
It can be said to be the longest phase of the cell cycle. During this phase the cell growth reaches its maximum size, replicates its DNA, prepares for cell division, and also performs it very cellular functions.
This stage has three parts which include: G1, G2 and S phases.
Some cells do not need to divide to exit the cell cycle. These cells can exit the cell cycle permanently. Example is a neurons, they may also exit the cell cycle temporarily. These cells are said to be in G0 which is not a stage of the cell cycle.
