Summary. While the left side of the heart becomes too weak to squeeze regular volumes of blood out of the heart when it pumps, this is known as systolic heart failure. Diastolic heart failure develops when the left side of the heart becomes too rigid to relax and fill with blood regularly.
Remember that burns are staged and rated from first to fifth degree, all based upon which layer of skin is damaged and burn't, with first covering the epidermis, second the dermis, third the muscular and fat, fourth charring the bone, and fifth causing amputation.
This is a third degree burn. Normally melting onto the flesh along with a charred, dry, and leathery look is characteristic of burns of the Third degree. Additionally third degree burns involve the muscle and fat tissues which is vascular so dilation of the blood vessels and fluid release cause severe dehydration, and in result hypovolemic (Blood Volume) shock.
The answer is 2, the condition of the environment affects everything it inhabitants.