The answer is D for this one
Numerous people.... Diabetics who are experiencing nerve degeneration of the extremities (something called Diabetic Neuropathy). Another group would be the elderly, who do loose sensation as age progresses. And lastly those with some sort of paralysis or peripheral nerve damage.
Explanation: Chemicals
There are four primary chemicals in the brain that effect happiness: dopamine, oxytocin, serotonin, and endorphins. By designing gamified experiences that activate these chemicals, you can increase your users' happiness and loyalty.
Explanation:
If I'm correct, mental health and physical health go hand in hand, if you are healthy mentally. Meaning, you're happy, not depressed and know how to take care of yourself mentally you are more likely to be health physically because you will have more motivation to keep yourself healthy, this also helps with self-esteem due to the fact, being mentally healthy means you have a good balance of self-esteem because you will understand mentally that a healthy balance of self-esteem will make your mind naturally want to be healthy physically and be mentally healthy as well. I hope this makes sense, if not tell me and I will simplify or explain a little better.