A mother's diet before conception can permanently affect how her child's genes function, according to a study published in Nature Communications. A 2003 study found that a female mouse's diet can change her offspring's coat color by permanently modifying DNA methylation.
Explanation:
ATP is the short form of Adenosine Triphosphate. The molecule is made up of three basic things:
- Adenine ring
- Ribose sugar
- Three phosphate groups(triphosphate)
This molecule is provides the energy needed for life processes when broken down.
The elements that makes up ATP are:
- Carbon(C)
- Hydrogen(H)
- Nitrogen(N)
- Oxygen(O)
- Phosphorus(P)
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Numerous antiepileptic medications, such phenytoin, have been designed to block voltage-gated sodium channels (VGSC) in neuronal membrane. In addition, multiple toxins and pharmacological modulators work by attaching to various biophysical states of the VGSC to cause their effects. Depending on how modulatory agents act, some VGSC states are stabilized or destabilized, altering the channel's biophysical properties. The first anticonvulsant to successfully treat epileptic disorders without causing undesirable side effects such as brain drowsiness was phenytoin.
Phenytoin has been indicated to block high-frequency neuronal activity potentials from the inner vestibule of the pore, as demonstrated by electrophysiological research and site-directed mutation.
Frequency and voltage both affect phenytoin binding.
There are theories that phenytoin interferes with the late sodium current that sustains depolarizations in epilepsy by blocking non-inactivated channels.
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