The first one answer is to be increased and the second one answer is to be decreased
The amino acids coded triplets in the 3' to 5' strand on the normalp53 gene of chromosome 13 are lysine, leucine, Glutamine, stop codons.
Explanation:
mRNA is formed by the transcription of DNA strand coding for a gene.
Any mutation in the DNA sequence even a difference of base pair would cause formation of different amino acids and hence altered protein.
The amino acid is formed in the step of translation where codes are read by tRNA on the mRNA strand and correct nucleotide is brought to growing polypeptide chain.
In transcription 3' to 5' strand acts a template strand. The amino acids on the p53 gene of chromosome 17 is
3'TTT AAC GTC ATC 5' Gene sequence
5' AAA UUG CAG UAG 3' mRNA
lysine, leucine, Glutamine, stop
