The correct answer is: Prokaryotic DNA is much smaller than eukaryotic DNA.
The first difference between prokaryotic and eukaryotic genome is its structure and complexity: Prokaryotic cells have a small amount of DNA in the form of a single, circular chromosome located in the cytoplasm, while eukaryotic cells have a nucleus and DNA arranged in multiple, linear chromosomes in it; eukaryotic cell has about 25 times more DNA than a prokaryotic cell. Differences in replication between prokaryotic and eukaryotic cells:
• point of origin
• direction- replication occurs in two opposing directions in prokaryotes while in eukaryotes it is unidirectional
• polymerases- in prokaryotes there are only one or two enzymes polymerases, while in eukaryotes four or more
• faster rate in prokaryotic cells.