Answer:
Total ATP molecules produced = 94 molecules of ATP
Explanation:
Myristoyl-CoA, is a saturated fatty acid with 14 carbons which has been activated for oxidation by attachment to coenzyme A. When it has undergone complete oxidation, it will yield 7 acetyl-CoA molecules and 6 FADH₂ and 6 NADH molecules each.
Each of the 7 acetyl-CoA molecules obtained from its initial oxidation enters into the citric acid cycle and is completely oxidized to yield further ATP and FADH₂ and NADH molecules.
The overall yield of ATP from the various enzymatic steps is shown below:
Acyl-CoA dehydrodenase = 6 FADH₂
β-Hydroxyacyl-CoA dehydrogenase = 6 NADH
Isocitrate dehydrogenase = 7 NADH
α-Ketoglutarate dehydrogenase = 7 NADH
Succinyl-CoA synthase = 7 ATP (from substrate-level phosphorylation)
Succinate dehydrogenase = 7 FADH₂
Malate dehydrogenase = 7 NADH
Note: 1 FADH2 molecule yields 1.5 ATP; 1 NADH molecule yields 2.5 ATP molecules. Therefore,
Total ATP from FADH₂ molecules = 13 * 1.5 = 19.5
Total NADH molecules = 27 * 2.5 = 67.5
Total ATP molecules produced = 19.5 + 67.5 + 7 = 94
Total ATP molecules produced = 94 molecules of ATP
