Systemic lupus erythematosus (SLE) is a rheumatic disease attributed to autoimmune mechanisms.
Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-tolerance with activation of autoreactive T and B cells, leading to the production of pathogen autoantibodies and tissue damage.
Innate immune mechanisms are required for aberrant adaptive immune responses in SLE. Recent advances in basic and clinical biology have shed new light on the disease mechanisms of lupus. This review article describes recent studies that provide valuable insights into disease-specific therapeutic targets.
Systemic lupus erythematosus (SLE or lupus) is a systemic autoimmune disease with inflammation of multiple organs. SLE is characterized by the production of pathogenic autoantibodies against nucleic acids and their binding proteins, reflecting a global loss of self-tolerance.
Loss of tolerance with subsequent immune dysregulation is the result of genetic factors in the context of environmental triggers and stochastic events, with recent studies implicating more than 30 genetic loci in disease pathogenesis.
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Answer:
love-love or just love
Explanation:
here why from a article i read before
At the beginning of the game, when both sides have no score, the game is love-love because in tennis, love means having a score of zero or nil. One point brings a player to 15, two to 30; and three to 40. The next point wins the game, unless a complex series of tiebreakers comes into play, because in order to win a tennis match, a player must win by a margin of two.
Where did the game gets its affectionate score for zero? The Oxford English Dictionary suggests that the term might be rooted in the colloquial phrase “for love,” meaning “without stakes being wagered.” This theory reflects the sport’s long history of etiquette and sportsmanship. Others theorize that love arose from the French word for “egg,” l’oeuf, because a zero on a scoreboard resembles an egg. This is a clever claim, but it remains unsubstantiated.
Answer: Off-season
Explanation:
This is the type of season that is dedicated to healing and rehabilitation and it is a very important season for every athlete. They are preparing for the next season during the off-season and there are many tips that can help in order to have a good recovery.
For example, rest your body, give your body time to heal from injuries, avoid hard workouts, and more.
The digital/phalangeal region encloses the fingers, and the thumb is called the pollex.
I hope this helps you and have a great day!! :)
