Difference Between Differentiation<span> & </span>Morphogenesis<span>. Multicellular </span>organisms<span> begin</span>life<span> as single </span>cells<span> called zygotes or spores, depending on the species. ...</span>Differentiation<span> is the process by which the </span>cells<span> take on their specific functions. </span>Morphogenesis<span> is the process by which an </span>organism<span> takes on its shape.