He demonstrated that SCD and sickle cell trait were due to the presence of abnormal 8-globin polypeptides in red blood cells. He demonstrated that the electrophhoretic mobility of B-globin from patients with SCD was different from that of healthy individuals. He demonstrated that both parents of multiple patients with SCD had low levels of sickled red blood cells. He hypothesized that SCD was a recessive trait and that the parents of patients with SCD would be heterozygous carriers. He demonstrated that the difference between B-globin polypeptides in individuals who were healthy and those with SCD is an amino acid substitution. He performed a peptide fingerprint analysis on B-globin from individuals with 84 84 and 89 88, which identified the segment of B-globin that was changed by the BS mutation. James Neel Linus Pauling Vernon Ingram
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A single stranded DNA (oligonucleotides) can hybridize with (d) both complementary DNA and complementary RNA.
DNA is the Deoxyribonucleic Acid. It is the genetic material present in majority of organisms. The nitrogenous bases present in DNA are: Adenine, thymine, Guanine and Cytosine. DNA is a double stranded structure hence it forms hydrogen bonds with a complementary strand. The complementary strand can be of a DNA or RNA.
RNA is the Ribonucleic Acid. It also is a genetic material present in very few organisms. RNA is less stable than the DNA and may be either single stranded or double stranded. The nitrogenous bases of RNA are: Adenine Uracil, Guanine and Cytosine.
To know more about DNA and RNA, here
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Both auxin and cytokinin are used to increase size of stem and fruits
