People with beriberi, a disease caused by thiamine deficiency, have elevated levels of blood pyruvate and a -ketoglutarate, espe

Question

Alchen [17]

3 years ago

14

People with beriberi, a disease caused by thiamine deficiency, have elevated levels of blood pyruvate and a -ketoglutarate, espe

cially after consuming a meal rich in glucose. How are these effects related to a deficiency of thiamine?

Biology

1 answer:

Ksivusya [100] · Answer 1 · 2022-02-10T03:08:52+03:00

Ksivusya [100]3 years ago

3 0

Answer:

Explanation:

Thiamine pyrophosphate is a thiamine derivative and acts a coenzyme for various enzymes including pyruvate dehydrogenase and α-ketoglutarate dehydrogenase. These are involved in catabolism of pyruvate and α-ketoglutarate, respectively.