Answer:
Here's what I get
Explanation:
You may have done a Williamson synthesis of guaifenesin by reacting guaiacol with 3-chloropropane-1,2-diol.
A. Mechanism
Step 1
NaOH converts guaiacol into a phenoxide ion.
Step 2
The phenoxide acts as the nucleophile in an SN2 reaction to displace the Cl from the alkyl halide.
B. Improve the yield
You probably carried out the reaction in ethanol solution — a polar protic solvent.
You might try doing the reaction in a polar aprotic solvent— perhaps DMSO.
A polar aprotic solvent does not hydrogen bond to nucleophiles, so they become stronger.
C. Another method of ether synthesis —dehydration of alcohols
Sulfuric acid catalyzes the conversion of primary alcohols to ethers.
This is also a nucleophilic displacement reaction.
Protonation of the OH converts it into a better leaving group.
Attack by a second molecule of alcohol forms the protonated ether.
A molecule of water then removes the proton.
When two plates push against each other shear stress will happem because they move in opposite directions. In this case the force of the stress pushes some of the crust in different directions. When this happens, a large part of the crust can break off, which makes the plate size smaller.
The concentration of a solution can be expressed in (4) <span>moles per liter~</span>
The slight positive charges on the hydrogen atoms in water molecules attract the slight negative charges on the oxygen atoms of the other water molecules
Mexican Texas<span> is the historiographical name used to refer to the era of </span>Texan<span> history between 1821 and 1836, </span>when it was part<span> of </span>Mexico<span>. </span>Mexico gained independence<span> from Spain in 1821 in </span>its war<span> of</span>independence<span>. Initially, </span>Mexican Texas<span> operated very similarly to Spanish </span>Texas<span>.</span>