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<h2>Sensorineural Hearing Loss</h2>
Explanation:
- Your ear is comprised of three sections—the external, the center, and the internal ear. Sensorineural hearing loss or SNHL, occurs after internal ear harm. Issues with the nerve pathways from your inward ear to your cerebrum can likewise cause SNHL. Delicate sounds might be difficult to hear. Significantly stronger sounds might be hazy or may sound stifled.
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This is the most widely recognized kind of permanent hearing loss. More often than not, medication or medical procedure can't fix SNHL. Listening devices may enable you to hear.
I'm pretty sure it would stick, because the balloon is mainly negatively charged, while the tissue paper is mainly positively charged.
Answer:
The order must be K2→K1, since the permanently active K1 allele (K1a) is able to propagate the signal onward even when its upstream activator K2 is inactive (K2i). The reverse order would have resulted in a failure to signal (K1a→K2i), since the permanently active K1a kinase would be attempting to activate a dead K2i kinase.
Explanation:
- You characterize a double mutant cell that contains K2 with type I mutation and K1 with type II
mutation.
- You observe that the response is seen even when no extracellular signal is provided.
- In the normal pathway, i f K1 activat es K2, we expect t his combinat ion of two m utants to show no response with or without ext racell ular signal. This is because no matt er how active K1 i s, it would be unable to act ivate a mutant K2 that i s an activit y defi cient. If we reverse the order, K2 activating K1, the above observati on is valid. Therefore, in the normal signaling pathway, K2 activates K1.
