Answer:
False
Explanation:
Approximately 200 out of 200 million sperms ejaculated during intercourse reach the general vicinity of the egg. They sperms must undergo capacitation during which dilute inhibitory factors fluids of the female reproductive tract weaken the membrane of the sperm head so that head of the sperm can be broken easily when it came in contact with the egg.
The first sperm to reach an egg isn’t the one to fertilize it because the egg is surrounded by a gelatinous membrane called the zona pellucida. Outside this layer, a layer of small granulosa cells also present.
Therefore, it requires numerous sperm to clear a path through these barriers before one of them can penetrate the egg and fertilize it.
Answer:
Aldehyde Dehydrogenase 2 (ALDH2) is an enzyme required to eliminate toxins such as acetaldehyde and alcohol, thereby mutations in this protein may be associated with the Alcohol flush syndrome (AFS)
Explanation:
ALDH2 is a protein required for ATP generation by catalyzing the oxidation of aldehydes to carboxylic acids (i.e., oxidation of NADH to NAD+). Mutations in the ALDH2 gene have been associated with the inactive form of this enzyme, and this specific mutation at position 487 alters its enzymatic activity associated with the metabolism of acetaldehyde and alcohol. This amino acid substitution may lead to the active site-directed inactivation of the enzyme.
