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abruzzese [7]
3 years ago
12

Qué tipo de anomalía cromosómica es el síndrome de down y Cómo se manifiesta? ¿Qué tipo de anomalía cromosómica es el síndrome d

e angelman y Cómo se manifiesta?
Biology
1 answer:
sashaice [31]3 years ago
5 0

Answer:

El síndrome de Down es el resultado de un niño nacido con un cromosoma adicional agregado al número esperado de cromosomas (generalmente destinado a ser 46).

El síndrome de Angelman se produce cuando un niño nace con una mutación en el 15º cromosoma heredado de los padres.

Explanation:

En el síndrome de Down, se agrega un cromosoma adicional al complemento de cromosomas que un niño debe heredar de sus padres. Se supone que un niño tiene un complemento de 46 cromosomas (23 cada uno) de ambos padres. Una vez que hay un aumento en este número, se establece el síndrome de down. Es una condición cromosómica común. Puede manifestarse como una trisomía, causada por la no disyunción durante la división celular, lo que resulta en 3 copias del cromosoma 21 en lugar de 2 copias, mosaicismo, donde una mezcla de células se clasifican en 2 grupos que contienen un complemento completo de 46 cromosomas y el otro un el cromosoma adicional lo hace 47 y la translocación ocurre cuando un cromosoma 21 adicional o parte del 21 se une al cromosoma 14. Los niños generalmente tienen cabezas y orejas pequeñas, cuellos cortos, caras planas, etc.

En el síndrome de Angelman, el cerebro se ve afectado en gran medida, debido al efecto de la mutación en el sistema nervioso. La pérdida de la función en el 15º cromosoma es responsable del síndrome de Angelman, que resulta en la incapacidad del niño para hablar, mantener el equilibrio, moverse, un desarrollo deficiente tanto física como intelectualmente.

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Suppose two independently assorting genes are involved in the pathway that determines fruit color in squash. These genes interac
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Answer:

100% yellow fruit color, Yyww.

Explanation:

<u>Available data</u>:

  • two independently assorting genes
  • the W allele codes for a dominant white phenotype
  • w allele codes for a colored squash
  • The allele Y codes for a dominant yellow phenotype
  • the allele y codes for a recessive green phenotype
  • The phenotypes from the first locus will always mask the phenotype produced by the second locus if the dominant allele (W) is present at the first locus. This masking pattern is known as dominant epistasis

Epistasis means "interruption" and refers to interactions between genes located in different loci in the same chromosome. An “epistatic gene” can alter, influence, or suppress the expression of a "hypostatic gene". When the epistatic gene is dominant, the interaction is known as "dominant epistasis".

W suppresses the expression of Y and y, this means that whenever W is present, the fruit is white. If W <u>is not</u> present, the fruit color can be expressed.

So, the proposed cross in the present problem occurs between a green fruited individual and yellow fruited individual, which suggests that W is absent.

<em>Genotype for Green fruit: yyww</em>

<em>Genotype for purebred Yellow fruit: YYww</em>

Cross:

Parental) YYww    x    yyww

Gametes) Yw  Yw  Yw  Yw  yw  yw  yw  yw

Punnet square)    Yw       Yw       Yw      Yw

                 yw    Yyww  Yyww  Yyww  Yyww

                 yw    Yyww  Yyww  Yyww  Yyww

                 yw    Yyww  Yyww  Yyww  Yyww

                 yw    Yyww  Yyww  Yyww  Yyww

F1) 100% Yellow fruited plants, Yyww

As these two genes assort independently, we can also represent the cross for each gene by separate, like this:

For w gene:

Parental) ww  x  ww

Gametes) w w w w

Punnet square)  w     w

                 w     ww   ww

                 w      ww  ww

F1) 4/4 or 100% colored-fruits

For Y gene:

Parental) YY  x  yy

Gametes) Y Y y y

Punnet square)  Y     Y

                 y     Yy     Yy

                 y     Yy     Yy

F1) 4/4 or 100% yellow fruits, Yy.

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