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Ad libitum [116K]
3 years ago
8

Where would a frameshift mutation cause the most damage?

Biology
1 answer:
tester [92]3 years ago
4 0

Answer:

All frameshift mutations are equal

Explanation:

Frameshift mutation is a type of mutation caused by insertion or deletion of nucleotide base(s) in a genetic sequence causing that sequence to be read in a different way from what was originally planned.

The bases in the sequence of a gene is read in three's (codon), however, when one or more bases is added (insertion) or removed (deleted), the reading frame is altered causing the sequence to be read in a completely different order that can result in a protein that is non-functional.

However, FRAMESHIFT MUTATION is so potent that it affects the sequence no matter where it occurs. In other words, the effect of all frameshift mutations are equal.

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Larval Stage

Frogs still in the larval stage, called tadpoles, are very different in outward appearance and internal physiology from their adult counterparts. Most notable is the presence of gills instead of lungs during this stage. Tadpoles can also take in oxygen through their skin, a trait that aids in gas exchange (bringing in oxygen and expelling carbon dioxide, as with lung respiration) while the tadpole is living completely underwater.

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Skin Respiration

An adult frog’s thin and permeable skin allows it to take in oxygen, even when completely submerged. Oxygen readily passes through this thin membrane-like skin, providing the frog with the oxygen it needs to stay alive under water without the need for gills. Because of the permeability of a frog’s skin, moisture is lost easily and most frogs must remain in a moist or humid environment in order to retain their water levels.

Lung Respiration

Compared with many other amphibians, frogs have relatively well-developed and complex lungs, which are subdivided and contain many alveoli—tiny sacs that are responsible for gas exchange within the lungs. Unlike mammals that control their breathing with the diaphragm, frogs use their mouths and nostrils in tandem to bring air into their lungs. When a frog breathes in, it lowers the floor of its mouth and relaxes its throat. Then it opens its nostrils to allow air to enter into the newly expanded mouth and throat, at which point the frog contracts its mouth floor and forces air into the lungs.

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