It would be completely false to say that both internal and external environments can modify or alter a gene. The correct option among the two options that are given in the question is the second option or the last option. I hope that this answer has come to your great help.
during an experiment you make observations to test the hypothesis and prediction
ITS Not A clearly that’s just a really dumb answer to chose and on top of that D is the correct one because they both are bonds that wrap around and it tells what the DNA is (: hope this helps!