The neuroendocrine system produces and releases hormones which are basically chemicals that travel via the bloodstream to specific organs in the body to control things like heart rate, glucose release rate, etc. This is how homeostasis in maintained.
I believe the answer is...a change in allele frequency over many generations!
Hope this helps!
The krebs cycle occurs in the mitochondrion
D. Understand your personal heritage and it's basis in cultural values