Which of the following is not true of integrin? Question 4 options: Integrin molecules serve as stable, permanent anchors that a
nchor a cell to the extracellular matrix. Integrins undergo extensive conformational changes on binding to molecules on either side of the plasma membrane. Certain intracellular chemical signals can activate integrins from inside the cell, causing them to reach out and grab hold of extracellular structures. When integrin binds to the extracellular matrix, it stretches into an extended, activated state to attach to molecules on the inside of the cell.
Integrin molecules serve as stable, permanent anchors that anchor a cell to the extracellular matrix.
Explanation:
Integrins are transmembrane protein receptors that attach the cell cytoskeleton to the extracellular matrix (ECM) in animal cells. These glycoproteins (integrins) are highly dynamic heterodimeric molecules that anchor cells in their position and transduce signals into and out of cells. Integrin-ligand binding activates signaling pathways that are involved in fundamental cellular functions including, among others, organization of the cell cytoskeleton, cell migration, regulation of the cell cycle, etc.
