1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
earnstyle [38]
3 years ago
12

A doctoral student in biology, Esther Mensah, is reviewing primary literature over RNAi interference as part of her literary res

earch for her proposal on decreasing the amount of abnormal white blood cell growth associated with acute myeloid leukemia (AML) using a murine (mouse) model. She is being provided with 10 AML mice courtesy of her mentor. Can you help her out with her proposal
Biology
1 answer:
sleet_krkn [62]3 years ago
4 0

Answer:

She might study the function of putative oncogenes and/or tumor suppressor genes in AML mice by transfecting small interfering RNAs (siRNAs) which are able to suppress the expression of genes of interest through the RNA interference (RNAi) pathway

Explanations:

The RNA interference (RNAi) pathway is a naturally occurring mechanism which is used in molecular biology laboratories to inhibit the expression of target genes. The RNAi technique consists of delivering small interfering double-stranded RNAs (siRNAs, 18-30 nucleotides in length) into the cells in order to inhibit the translation of genes and/or trigger mRNA degradation, thereby suppressing target gene expression. These siRNAs are specifically designed to bind by complementarity to transcripts of target genes (i.e., mRNAs). In this case, the RNAi pathway can be used to study the function of genes involved in AML pathways (e.g., apoptosis, cell proliferation, etc).

You might be interested in
If we pick a plant and an animal cell, which one of them would lose its shape
maria [59]

Answer:

the animal cell would lose its shape as the plant cell has a cell wall which gives shape and protection.

by the animal cell don't have a cell wall.

hope it was helpful

Explanation:

4 0
3 years ago
Describe the steps in transcription that require complementary base pairing.
nalin [4]

Answer:

Explanation:

Transcription takes place in nucleus in the presence of the enzyme RNA polymerase.

During transcription, the code present in DNA gets transcribed into the code in mRNA.  (messenger RNA)

RNA even though is a single stranded shows base pairing.

The pre-mRNA gets created from the DNA.

DNA has two strands, one of these strands acts as coding and another non coding strand.

The DNA shows base pairing with AGTC.   [A-Adenine, G- Guanine, T-Thymine and C- Cytosine]

Whereas mRNA base pairing with AGUC.  [ U- Uracil ]

Here in mRNA, instead of thymine, uracil gets paired.

According to base pairing of coding strand/sense strand of DNA, complementary bases pairs in 5'---->3' direction in mRNA.

The mRNA created looks exactly like the non-coding strand/sense strand of DNA except instead of thymine, uracil gets replaced.

The pre-RNA undergoes splicing, capping and tailing to form mature mRNA.

5 0
4 years ago
The lateral line system provides ________ with a sense of distant touch, enabling these animals to sense objects that reflect pr
sineoko [7]
The lateral line system provides tactile sense organs ( that is from cyclostome fishes to amphibians or the aquatic vertebrates) with a sense of distant touch, enabling these animals to sense objects that reflect pressure waves and low-frequency vibration. This system made up of multiple of neuromasts. 
6 0
3 years ago
how do you go throght the life cycle throught metamorphasis and then inside the water cycle preticipating RAIN!!!!
Margaret [11]

Answer:

precipitation, condensation, evaporation, soemthing else, water, clouds, surface ruunoff, etc

Explanation:

hope it helped on science

6 0
2 years ago
Read 2 more answers
If a bowling ball hits a wall with a force of 6 N, the wall exerts a force of ____ back on the bowling ball. (1 point) 0 N 3 N 6
alexgriva [62]
The answer is 6 Newtons
7 0
3 years ago
Other questions:
  • Between ________ degrees fahrenheit, bacteria will multiply the most rapidly.
    12·1 answer
  • Mary marries an unaffected man, Justin, whose paternal uncle has galactosemia. Determine th genotypes for Justin’s Family
    12·1 answer
  • Around _____ of women have severe vaginal or pelvic pain during sexual intercourse for up to one year after giving birth.
    5·2 answers
  • ____________ fats tends to increase blood cholesterol levels, are solid at room temperature, and are found mostly in meat and da
    12·1 answer
  • Which of the following describes how the winter season affects organisms in the tundra biome?
    6·2 answers
  • Which of the following is true concerning sources of water pollution?
    9·2 answers
  • What is causing the roots of a plant to grow downward
    7·1 answer
  • What is the name of the sugar found in DNA nucleotides?
    13·2 answers
  • What type of traits are considered polygenic traits?
    8·1 answer
  • Need help with this
    8·2 answers
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!