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earnstyle [38]
3 years ago
12

A doctoral student in biology, Esther Mensah, is reviewing primary literature over RNAi interference as part of her literary res

earch for her proposal on decreasing the amount of abnormal white blood cell growth associated with acute myeloid leukemia (AML) using a murine (mouse) model. She is being provided with 10 AML mice courtesy of her mentor. Can you help her out with her proposal
Biology
1 answer:
sleet_krkn [62]3 years ago
4 0

Answer:

She might study the function of putative oncogenes and/or tumor suppressor genes in AML mice by transfecting small interfering RNAs (siRNAs) which are able to suppress the expression of genes of interest through the RNA interference (RNAi) pathway

Explanations:

The RNA interference (RNAi) pathway is a naturally occurring mechanism which is used in molecular biology laboratories to inhibit the expression of target genes. The RNAi technique consists of delivering small interfering double-stranded RNAs (siRNAs, 18-30 nucleotides in length) into the cells in order to inhibit the translation of genes and/or trigger mRNA degradation, thereby suppressing target gene expression. These siRNAs are specifically designed to bind by complementarity to transcripts of target genes (i.e., mRNAs). In this case, the RNAi pathway can be used to study the function of genes involved in AML pathways (e.g., apoptosis, cell proliferation, etc).

You might be interested in
The process shown here is called ____. The resulting offspring, Dolly, would be genetically identical to the ____. This is becau
Mama L [17]

Answer:

cloning, Finn-Dorset, DNA, nucleus

Explanation:

So basically what they're doing here is they're taking the cytoplasm of a cell of the Scottish Blackface sheep (maybe a lamb?, whatever)/removing the nucleus inside that cell and instead inserting the nucleus of the Finn-Dorset sheep. Then they insert that "integrated" cell (so to speak) into a surrogate ewe so that the blastocyst can evolve and develop into Dolly (the lamb/sheep).

The process is cloning. The resulting offspring would be genetically identical to the Finn-Dorset (sheep/lamb) b/c the nucleus is coming from that sheep & the nucleus has the genetic material (DNA).  Hope ya found this helpful :)

P.S. Oh yeah, and thanks for the fifty points (hopefully)

6 0
3 years ago
Dna that contains genes from more than one organism is called
Vlad1618 [11]

Answer:

DNA that contains genes from more than one organism is called "Recombinant DNA".

4 0
3 years ago
*BRAINLIEST*The diagram below shows the branching tree diagram for humans. The text box below it shows the set of derived shared
Inga [223]

Answer:

I would write "terrestrial/lives on land during all life stages" between the frog and pigeon branches.

Explanation:

Jaw evolution has started with fish, so i'd place that before the perch, evolution of four limbs is next and I would plate it between the perch and the frog. Evolution of an egg has ensured that organisms remain terrestrial during all stages of life and don't need to rely on water to lay their eggs. So I would place that between the frog and the pigeon. True mammary glands and true hair, as we know it formed on mammals so i'd place that between the pigeon and the rats (although synapsids evolved similar structures long before birds even existed). And lastly, I would place "walking on two legs" between rats and human branches. Because our ancestors evolved bipedalism relatively late.

8 0
4 years ago
A female fly that has miniature wings and sepia eyes is crossed with a male that has normal wings and is homozygous for red eyes
Eduardwww [97]

Answer and Explanation:

  • The gene that expresses the size of the wing is X-linked. The dominant allele expresses long wings, XM, while the recessive allele expresses miniature wings, Xm.  
  • The gene that expresses the color of the eyes is autosomal. The dominant allele expresses red color, S, and the recessive allele expresses sepia color, s.

A <em>female fly</em> that has <em>miniature wings and sepia eyes</em> (<em>XmXm ss</em>) is crossed with a <em>male</em> that has <em>normal wings and is homozygous for red eyes (XMY SS). </em>

The F1 are intercrossed to produce the F2.

1º Cross:

Parental) XmXm ss    x    XMY SS

Gametes) Xms   Xms     Xms   Xms  

                XMS   XMS    YS    YS

Punnet Square)    Xms           Xms            Xms             Xms

                XMS   XMXmSs    XMXmSs   XMXmSs    XMXmSs

                XMS   XMXmSs    XMXmSs   XMXmSs    XMXmSs

                YS      XmY Ss      XmY Ss       XmY Ss       XmY Ss

                YS      XmY Ss      XmY Ss       XmY Ss       XmY Ss

F1) 1/2 or 50% of the progeny are females and the other 1/2 or 50% are males

  100% of the females (1/2 or 50% of the progeny) are long-winged and  red-eyed

    100% of the males (1/2 or 50% of the progeny) are miniature.winged and red-eyed.

2º Cross:

Parental) XMXm Ss      x      XmY Ss

Gametes) XMS   XMs  XmS  Xms

                XmS   Xms  YS    Ys

Punnet Square)       XMS             XMs          XmS             Xms

                  XmS    XMXm SS  XMXm Ss   XmXm SS   XmXm Ss

                  Xms    XMXm Ss   XMXm ss   XmXm Ss    XmXm ss

                   YS      XMY SS     XMY Ss      XmY SS        XmY Ss

                   Ys       XMY Ss     XMY ss       XmY Ss        XmY ss

F2) 8/16=4/8=1/2 or 50% of the progeny are females and the other 1/2 or 50% are males

<u><em>Females (8/16)</em></u>:    

  • 3/8 of the females are long-winged and red-eyed, XMX- S-
  • 1/8 of the females are long-winged and sepia-eyed, XMX- ss
  • 3/8 of the females are miniature-winged and red-eyed, XmXm S-
  • 1/8 of the females are miniature-winged and sepia-eyed, XmXm ss

<u><em>Males (8/16)</em></u>:    

  • 3/8 of the males are long-winged and red-eyed, XMY S-
  • 1/8 of the males are long-winged and sepia-eyed, XMY ss
  • 3/8 of the males are miniature-winged and red-eyed, XmY S-
  • 1/8 of the males are miniature-winged and sepia-eyed, XmY ss  

Note: The symbol "-" means that in its place might be a recessive allele or a dominant allele. For example, <em>S-</em> means that it might be <em>SS</em> or <em>Ss</em>.  

4 0
3 years ago
Sperm whales, a(n) species, maintain their populations close to carrying capacity.
soldier1979 [14.2K]
The answer is K-selected.

<span>The population size of K-selected species is fairly constant in time, unlike the population size of r-selected species. r-selected species are usually bellow carrying capacity and the population size is density independent. On the contrary, K-selected species are usually near or at carrying capacity and the population size is density dependent. It can be concluded that sperm whales have K-selected populations, since they </span><span>maintain their populations close to carrying capacity.</span>

4 0
3 years ago
Read 2 more answers
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