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earnstyle [38]
3 years ago
12

A doctoral student in biology, Esther Mensah, is reviewing primary literature over RNAi interference as part of her literary res

earch for her proposal on decreasing the amount of abnormal white blood cell growth associated with acute myeloid leukemia (AML) using a murine (mouse) model. She is being provided with 10 AML mice courtesy of her mentor. Can you help her out with her proposal
Biology
1 answer:
sleet_krkn [62]3 years ago
4 0

Answer:

She might study the function of putative oncogenes and/or tumor suppressor genes in AML mice by transfecting small interfering RNAs (siRNAs) which are able to suppress the expression of genes of interest through the RNA interference (RNAi) pathway

Explanations:

The RNA interference (RNAi) pathway is a naturally occurring mechanism which is used in molecular biology laboratories to inhibit the expression of target genes. The RNAi technique consists of delivering small interfering double-stranded RNAs (siRNAs, 18-30 nucleotides in length) into the cells in order to inhibit the translation of genes and/or trigger mRNA degradation, thereby suppressing target gene expression. These siRNAs are specifically designed to bind by complementarity to transcripts of target genes (i.e., mRNAs). In this case, the RNAi pathway can be used to study the function of genes involved in AML pathways (e.g., apoptosis, cell proliferation, etc).

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Answer:

Tt and tt

Explanation:

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2 years ago
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LekaFEV [45]

Answer:D.D.) Suspend the cells in liquid agar culture and monitor which culture continues to grow.

Explanation

Options A-C are correct except D.

→Increase in Telomere length is indicative of abnormal growth, cancer cells can reactive  telomerase to increase cell's length.

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Uncontrolled cell division is an indication of virulent growth in mutated cells.

<u>Cancer cell requires a ,medium of  living host to thrive, alga medium will not support growth for carcinoma cells -the correct answer. </u>

<u></u>

Completed Que.

:Imagine that you are a graduate student working in a cancer lab. You accidentally mix unlabeled tubes of carcinoma cells with tubes of normal epithelial cells. Which of the following is NOT a possible strategy to allow you to distinguish which tubes contain carcinoma cells?

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D.) Suspend the cells in liquid agar culture and monitor which culture continues to grow.

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3 years ago
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